08-13-2025 Dealing with poop stains on bed sheets can be challenging but manageable. Using enzyme-based laundry detergent combined with proper pre-treatment, cold rinsing, and careful washing techniques effectively removes stains and odors without damaging fabrics. Avoid drying until stains are fully removed to prevent permanent damage. This article details the process, tips, and answers common questions to help keep your bedding fresh and hygienic.